学術論文

2018

  • 23) Covalent Modification of Phosphatidylethanolamine by Benzyl Isothiocyanate and the Resultant Generation of Ethanolamine Adduct as Its Metabolite. Nakamura T, Hirakawa M, Nakamura Y, Ishisaka A, Kitamoto N, Murakami A, Kato Y. Chem. Res. Toxicol.  [Epub ahead of print] 
           PMID: 30735032.

  • 22) Assessing self-reported green tea and coffee consumption by food frequency questionnaire and food record and their association with polyphenol biomarkers in Japanese women. Takechi R, Alfonso H, Harrison A, Hiramatsu N, Ishisaka A, Tanaka A, Tan L, Lee AH. Asia Pac J Clin Nutr. 27, 460-465, 2018.
           PMID: 29384336.


2017

  • 21) Cytotoxic and cytoprotective effects of tryptamine-4,5-dione on neuronal cells: a double-edged sword. Suga N, Murakami A, Nakamura Y, Ishisaka A, Kitamoto N, Ito M, Kato Y. Free Radic Res. 51, 545-553, 2017.
           PMID: 28503967. 
  • 20) In vivo absorption and metabolism of leptosperin and methyl syringate, abundantly present in manuka honey. Ishisaka A, Ikushiro S, Takeuchi M, Araki Y, Juri M, Yoshiki Y, Kawai Y, Niwa T, Kitamoto N, Sakaki T, Ishikawa H, Kato Y. Mol. Nutr. Food Res. 1700122, 2017.
           PMID: 28444960.

2016

  • 19) A novel quinone derived from 5-hydroxyindoleacetic acid reacts with protein: Possible participation of oxidation of serotonin and its metabolite in the development of atherosclerosis. Kato Y, Oki K, Suga N, Ono S, Ishisaka A, Miura Y, Kanazawa S, Naito M, Kitamoto N, Kettle AJ. Free Radic Biol Med. 101, 500-510, 2016.
            PMID: 27856348.
  • 18) Metal-catalyzed oxidation of 2-alkenals generates genotoxic 4-oxo-2-alkenals during lipid peroxidation. Nuka E, Tomono S, Ishisaka A, Kato Y, Miyoshi N, Kawai Y. Biosci Biotechnol Biochem. 80, 2007-2013, 2016.

PMID: 27281652.

  • 17) Characterization of a Monoclonal Antibody against Syringate Derivatives: Application of Immunochemical Detection of Methyl Syringate in Honey. Kato Y, Fujinaka R, Juri M, Yoshiki Y, Ishisaka A, Kitamoto N, Nitta Y, Ishikawa H. J Agric Food Chem. 64, 6495-6501, 2016.

PMID: 27477590.

  • 16) Plasma concentrations of coffee polyphenols and plasma biomarkers of diabetes risk in healthy Japanese women. Lee AH, Tan L', Hiramatsu N, Ishisaka A, Alfonso H, Tanaka A, Uemura N, Fujiwara Y, Takechi R. Nutr Diabetes. 6, e212, 2016.

PMID: 27270110.

  • 15) Competitive immunochromatographic assay for leptosperin as a plausible authentication marker of manuka honey. Kato Y, Araki Y, Juri M, Ishisaka A, Nitta Y, Niwa T, Kitamoto N, Takimoto Y. Food Chem. 194, 362-365, 2016.

PMID: 26471566.

  • 14) Elevated plasma and urinary concentrations of green tea catechins associated with improved plasma lipid profile in healthy japanese woman. Takechi R, Alfonso H, Hiramatsu N, Ishisaka A, Tanaka A, Tan L, Lee AH. Nutr. Res. 36, 220-226, 2016.

PMID: 26923508.

 

2015

  • 13) Quercetin and related polyphenols: new insights and implications for their bioactivity and bioavailability. Kawabata K, Mukai R, Ishisaka A. Food Funct. 6, 1399-1417, 2015.

PMID: 25761771.

2014

  • 12) Immunochemical authentication of manuka honey using a monoclonal antibody specific to a glycoside of methyl syringate. Kato Y, Araki Y, Juri M, Fujinaka R, Ishisaka A, Kitamoto N, Nitta Y, Niwa T, Takimoto Y. J Agric Food Chem. 62, 10672-10678, 2014.

PMID: 25310890.

  • 11) Plausible Authentication of Manuka Honey and Related Products by Measuring Leptosperin with Methyl Syringate.Kato Y, Fujinaka R, Ishisaka A, Nitta Y, Kitamoto N, Takimoto Y. J Agric Food Chem. 62, 6400-6407, 2014.

PMID: 24941263.

  • 10) Specific localization of quercetin-3-O-glucuronide in human brain. Ishisaka A, Mukai R, Terao J, Shibata N, Kawai Y. Arch Biochem Biophys. 557, 11-17, 2014.

PMID: 24893148.

 

2013

  • 9) Mitochondrial dysfunction leads to deconjugation of quercetin glucuronides in inflammatory macrophages. Ishisaka A, Kawabata K, Miki S, Shiba Y, Minekawa S, Nishikawa T, Mukai R, Terao J, Kawai Y. PLoS One.19, e80843, 2013.

PMID: 24260490.

  • 8) Non-specific protein modifications by a phytochemical induce heat shock response for self-defense. Ohnishi K, Ohkura S, Nakahata E, Ishisaka A, Kawai Y, Terao J, Mori T, Ishii T, Nakayama T, Kioka N, Matsumoto S, Ikeda Y, Akiyama M, Irie K, Murakami A. PLoS One. 8, e58641, 2013.

PMID: 23536805.

 

2012

  • 7) Blueberry intervention improves vascular reactivity and lowers blood pressure in high-fat-, high-cholesterol-fed rats. Rodriguez-Mateos A, Ishisaka A, Mawatari K, Vidal-Diez A, Spencer JP, Terao J. Br J Nutr. 9, 1-9, 2012.

PMID: 23046999.

  • 6) Effect of quercetin and its glucuronide metabolite upon 6-hydorxydopamine-induced oxidative damage in Neuro-2a cells. Mukai R, Kawabata K, Otsuka S, Ishisaka A, Kawai Y, Ji ZS, Tsuboi H, Terao J. Free Radic. Res. 46, 1019-1028, 2012.

PMID: 22404304.

 

2011

  • 5) Accumulation of orally administered quercetin in brain tissue and its antioxidative effects in rats. Ishisaka A, Ichikawa S, Sakakibara H, Piskula MK, Nakamura T, Kato Y, Ito M, Miyamoto KI, Tsuji A, Kawai Y, Terao J. Free Radic. Biol. Med. 51, 1329-1336, 2011.

PMID: 21741473.

  • 4) Effect of quercetin and glucuronide metabolites on the monoamine oxidase-A reaction in mouse brain mitochondria. Yoshino S, Hara A, Sakakibara H, Kawabata K, Tokumura A, Ishisaka A, Kawai Y, Terao J. Nutrition. 27, 847-852, 2011.

PMID: 21371861.

 

2009

  • 3) Different profiles of quercetin metabolites in rat plasma: comparison of two administration methods. Kawai Y, Saito S, Nishikawa T, Ishisaka A, Murota K, Terao J. Biosci. Biotechnol. Biochem. 73, 517-523, 2009.

PMID: 19270373.

 

2008

  • 2) Flavonoids as substrates and inhibitors of myeloperoxidase: molecular actions of aglycone and metabolites. Shiba Y, Kinoshita T, Chuman H, Taketani Y, Takeda E, Kato Y, Naito M, Kawabata K, Ishisaka A, Terao J, Kawai Y. Chem. Res. Toxicol. 21, 1600-1609, 2008.

PMID: 18620432.

  • 1) Immunochemical detection of flavonoid glycosides: development, specificity, and application of novel monoclonal antibodies. Kawai Y, Ishisaka A, Saito S, Uchida K, Shibata N, Kobayashi M, Fukuchi Y, Naito M, Terao J. Arch. Biochem. Biophys. 476, 124-132, 2008.

PMID: 18267102.